Research Insights - September 01, 2014

The Exploration of Therapeutic Proteins

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Prof. ZHANG Mingjie, IAS Senior Fellow and Kerry Holdings Professor of Science (Middle) and the IAS HKUST-Scripps researchers (From left: WANG Feng, Carol LAU, XU Zhiwen and Cario LO).
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The IAS HKUST-Scripps R&D Laboratory is also led by Prof. Paul SCHIMMEL, IAS Visiting Professor and Ernest and Jean Hahn Professor of Molecular Biology and Chemistry at the Scripps Research Institute.
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The laboratory developed an aminoacyl tRNA synthetases (AARS) transcriptome enrichment method and used high throughput deep sequencing to comprehensively identify new AARS variants.

IAS HKUST - Scripps R&D Lab reveals its achievements in recent researches on therapeutic proteins, including a systematic methodology for discovery of novel naturally-occurring splice variants and characterization of their biological activities. In addition, it also highlights how scientific computation and "big data" come into play. 

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